Research at Molbel
Nanobiotechnology:

Dendrimer-like DNA.
(Bar = 100 nm)

We have made some extremely interesting and intriguing nanostructures and nanomaterials.

Stay tuned!!

 

Nucleic Acid Engineered Materials (NAEM) can be synthesized in a precisely controlled fashion at the nanoscale. Current projects include:

NAEM nanobarcodes
NAEM nanopatterning
NAEM nanoheaters
NAEM nanowires
NAEM nanomotors
NAEM hybrid materials

Related publications:

S. Um, S. Kwon, J. Lee and D. Luo, Dendrimer-like DNA based, self-assembled nanoscale hollow buckyballs. Submitted (2005)

Y. Li, Y. Cu and D. Luo, DNA fluorescence nanobarcodes for multiplexed pathogen detection, Under review by Nature Biotechnology (2005)

K.O. Freedman, J. Lee, Y. Li, D. Luo, V.B. Skobeleva, and P.C. Ke, Diffusion of Single Star-Branched Dendrimer-Like DNA, Revision submitted to J. of Phy. Chem. B. (2005)

L. Moreau, P. Barthélémy, Y. Li, D. Luo, and M.W. Grinstaff, Nucleoside Phosphocholine Amphiphile for in vitro DNA transfection, Submitted (2005)

S.M. Stavis, J.B. Edel, Y. Li, K.T. Samiee, D Luo and H.G. Craighead, Detection and identification of nucleic acid engineered fluorescent labels in submicrometer fluidic channels, Nanotechnology, in press (2005)

R. A. Gemeinhart, D. Luo, and W. M. Saltzman, Cellular fate of a modular DNA delivery system mediated by silica nanoparticles, Biotechnology Progress, in press, (2005)

C.A.H. Prata, Y. Zhao, P. Barthélémy, Y. Li, D. Luo, T.J. McIntosh, S.J. Lee, and M.W. Grinstaff. Charge-reversal amphiphiles for gene delivery. J Am Chem Soc 126(39): 12196-7 (2004)

Y. Li, Y.D. Tseng, S.Y. Kown, L. d’Espaux, J.S. Bunch, P.L McEuen and D. Luo. Controlled assembly of dendrimer-like DNA. Nature Materials, 3, 38-42 (2004).

D. Luo, Ernest Han, Nadya Belcheva and W. Mark Saltzman, A self-assembled, modular DNA delivery system mediated by silica nanoparticles J. of Control. Release. 95, 333-341 (2004)

D. Luo, K. Haverstick, N. Belcheva, E. Han and W.M. Saltzman. Poly(ethylene glycol)-conjugated dendrimer for biocompatible and high efficient DNA delivery, Macromolecules, 35, 3456-3462 (2002)

 

Molecular BioEngineering Lab | Copyright © 2003 Molbel